Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

In this study, we assessed the efficacy and safety of four skin care products indicated for skin hydration (Aqua Therapy and Perfecta), skin aging (Unica Resurfacing Therapy) and sensitive skin (Comfort Therapy), in four groups of 7 volunteers with different skin types. These products belong to four skin care ranges (Aqua, Perfecta, Unica and Comfort) and are formulated with a specific combination of active compounds (Dermo28). Evaluation of sebum secretion, hydration and pH of the skin (all groups), wrinkle severity (Unica Resurfacing Therapy) and erythema (Comfort Therapy) was performed at baseline and after 4 weeks of treatment. A significant increase in hydration was recorded in subjects with dry skin receiving Aqua Therapy for facial hydration and Perfecta for body hydration, respectively (p < 0.001 for both). A significant decrease in the modified Fitzpatrick wrinkle scale (p = 0.006) and an increase in sebum secretion and hydration (p = 0.013 and p < 0.001, respectively) were observed in the Unica Resurfacing Therapy group. In subjects with sensitive skin (Comfort Therapy), a decrease in erythema (p = 0.012), an increase in sebum secretion (p = 0.001) and hydration (p < 0.001), and a reduction in pH (p = 0.005) were detected at the end of treatment. Only one patient reported a minor adverse event. This specific combination of active ingredients was clinically effective and safe, and contributed to skin surface hydrolipidic film regeneration, improvement of wrinkle depth and reduction of redness.